RUMORED BUZZ ON BLOCK PAIN RECEPTORS WITH PROLEVIATE

The activation of CB1 and CB2 inhibits the formation of intracellular cAMP, for this reason resulting in an incredible reduction from the excitatory impact within the neurons [88,89]. On top of that, the activation of CB2 can further reduce the mast cell degranulation and the discharge of pro-inflammatory mediators, generating the reduction in pain